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Lasers switch on drugs

  July 21/28, 2008
A drug that's activated when its molecules are hit by two photons simultaneously makes it possible to precisely control where in the body the drug takes effect. Target intense pulses of laser light at a specific place in the body and you've got enough simultaneous hits to switch on the drug.

An experiment with mice showed that the technique can be used to selectively close blood vessels.

Two-photon drugs could be used to treat cancer and other diseases.

Research paper:
Blood-Vessel Closure Using Photosensitizers Engineered for Two-Photon Excitation
Nature Photonics, July 2008

Researchers' homepages:
Anderson Research Group
Brian C. Wilson
David Phillips
Rebane Group

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