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Tiny microscope goes with the flow

  August 4/11, 2008
Position a series of microscopic pinholes over digital camera pixels and you have a microscope-on-a-biochip without the bulky lenses of traditional microscopes. The microscope captures images of cells and microorganisms as they flow across the chip.

The optofluidic microscopy biochip was used to characterize mutant strains of the microscopic worm C. elegans and take images of single cell organisms.

The microscope biochip could be used for medical and biological research.

Research paper:
Lensless High-resolution On-chip Optofluidic Microscopes for Caenorhabditis Elegans and Cell Imaging
Proceedings of the National Academy Of Sciences, published online July 28, 2008

Researchers' homepages:
Biophotonics Laboratory
Sternberg Lab
Demetri Psaltis

Related stories and briefs:
Speck-sized microscope nears -- a microscope-on-a-chip that uses traditional lenses

Back to TRN August 4/11, 2008

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