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Biochip
tracks molecular signals
The "chemistrode" is the biochemical equivalent of an electrode; it records molecular signals from microscopic spaces at short time intervals. A double chemistrode has captured chemical signals that are 15 thousandths of a millimeter apart and sampled as frequently as two thirds of a second.
The biochip injects, then captures tiny plugs of fluids. Injected plugs stimulate biological samples. Captured plugs are analyzed to determine the changing flow of chemicals coming from biological samples.
The biochip promises to make it easier to study the subtle biochemical flows involved in life's processes.
Research paper:
The Chemistrode: A Droplet-based Microfluidic Device for Stimulation and Recording with High Temporal, Spatial, and Chemical Resolution
Proceedings of the National Academy Of Sciences, November 4, 2008
Researchers' homepages:
Ismagilov Group
Andrey Kuznetsov
Louis Philipson
Related stories and briefs:
Coated nanotubes make biosensors -- related research
Tiny transistors sniff chemicals -- related research
Back to TRN November 10/17, 2008
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