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DNA
with the naked eye
Researchers
have come a long way in being able to detect subtle details of DNA molecules
that show disease or susceptibility to diseases, but the detection methods
usually involve sophisticated laboratory equipment that's beyond the reach
of most medical clinics and much of the developing world. A DNA microarray that uses electrostatic interaction between microscopic glass spheres and DNA molecules on the surface of a biochip to detect specific types of DNA makes it possible to observe the results with the unaided eye. The device has the potential to spread advanced medical diagnostics and research well beyond well-funded laboratories.
Research paper:
Electrostatic Readout of DNA Microarrays with Charged Microspheres
Nature Biotechnology, published online June 29, 2008
Researchers' homepages:
Nathan Clack
Jay T. Groves
Related stories and briefs:
Snip-and-tag DNA sequencing
Parallel processing of DNA
Back to TRN July 7/14, 2008
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