Synthetic protein folding

   July 7/14, 2008
Life's myriad biochemical processes depend on the type of molecule, the molecule's shape, and how the shape changes in response to the environment. A synthetic molecule that toggles between mirror-image shapes marks a major advance in efforts by scientists to mimic the biology of protein folding.

The synthetic molecule is a catalyst that hydrogenates fats. The shape-changing technique promises to speed the development of catalysts for all kinds of chemical processes.

Research paper:
Conformationally Driven Asymmetric Induction of a Catalytic Dendrimer
Journal of the American Chemical Society, June 25, 2008

Researchers' homepages:
T. V. RajanBabu
Jon R. Parquette

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