Tiny drug capsules shine

April 23/30, 2003

German and Russian researchers have made a microcapsule that is able to communicate its progress in delivering drugs to biological tissue.

The microcapsule communicates via light waves. The key was finding nontoxic materials that emit infrared light at wavelengths that can easily be measured because they are not absorbed by water and biological tissue.

The researchers' prototype microcapsules include some that emit a single wavelength, or color, and others that emit several in the 750- to 1200-nanometer range. These could eventually be used to monitor combinations of drugs. Visible light ranges from 400-nanometer blue to 700-nanometer red.

They made the microcapsules by causing oppositely-charged layers of material to form a shell around carbonate particles 3.7 microns in diameter, which is a little smaller than red blood cell. The researchers added negatively charged light-emitting nanocrystals, which, attracted by positively-charged portions of the microcapsule, embedded in the shell. They dissolved the carbonate particles to leave hollow microcapsules.

The microcapsules could be ready for use in five years, according to the researchers, who are from the University of Hamburg and Max Planck Institute in Germany, and the Russian National Research Center for Antibiotics. The work appeared in the March 12, 2003 issue of Nano Letters.

Page One

Nanocomputer skips clock

DNA motor keeps cranking

Software sorts tunes

Silver bits channel nano light

News briefs:
Tiny drug capsules shine
Degree of difference sorts data
Casting yields non-carbon nanotubes
Material makes backwards lens
Juiced liquid jolts metal into shapes
Nanotube web could mimic brain

Research Watch blog

View from the High Ground Q&A
How It Works

RSS Feeds:
News  | Blog

Ad links:
Buy an ad link


Ad links: Clear History

Buy an ad link

Home     Archive     Resources    Feeds     Glossary
TRN Finder     Research Dir.    Events Dir.      Researchers     Bookshelf
   Contribute      Under Development     T-shirts etc.     Classifieds

© Copyright Technology Research News, LLC 2000-2010. All rights reserved.