Microneedles give painless shots

December 3/10, 2003

The smaller the hypodermic needle, the less it hurts when it pierces skin.

Researchers from the Georgia Institute of Technology have developed ways to manufacture solid and hollow metal, silicon, plastic and glass microneedles that range in size from one millimeter to one thousandth of a millimeter.

The researchers demonstrated that an array of 400 microneedles can be used to pierce human skin, and successfully used a similar micro array to deliver insulin to diabetic rats.

Solid microneedles could eventually be used with drug patches to increase diffusion rates; hollow needles could eventually be used with drug patches and timed pumps to deliver drugs at specific times, according to the researchers.

The hollow needle designs include tapered and beveled tips, and could eventually be used to deliver microliter quantities of drugs to very specific locations.

The researchers' method involves etching microneedle masters from silicon, then using the masters to fabricate micromolds for metal and polymer needles. They made glass microneedles using conventional drawn-glass techniques.

Microneedle-based devices could be on the market within five years, according to the researchers. The work appeared in the November 17, 2003 issue of the Proceedings of the National Academy of Sciences.

Page One

Biochip puts it all together

DNA assembles nanotube transistor

Software paraphrases sentences

Chaotic lasers lock messages

Nanotubes detect nerve gas
Microneedles give painless shots
Layers promise cheap storage
Molecule makes two-step switch
Spin material handles heat
Carbon boosts plastic circuits

Research Watch blog

View from the High Ground Q&A
How It Works

RSS Feeds:
News  | Blog

Ad links:
Buy an ad link


Ad links: Clear History

Buy an ad link

Home     Archive     Resources    Feeds     Glossary
TRN Finder     Research Dir.    Events Dir.      Researchers     Bookshelf
   Contribute      Under Development     T-shirts etc.     Classifieds

© Copyright Technology Research News, LLC 2000-2010. All rights reserved.